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IMCS/Publications/CSJM/Issues/CSJM v.23, n.3 (69), 2015/

Classification of Early Stages of NAFLD Based on Dual Diagnostic Methods

Authors: Secrieru Iulian, Cojocaru Svetlana, Gaindric Constantin, Popcova Olga, Svetlana Țurcan
Keywords: Non-alcoholic fatty liver, NAFLD diagnostics, medical ultrasound, hepatologist/gastroenterologist, pathological liver states classification

Abstract

High prevalence of non-alcoholic fatty liver disease (NAFLD) has made this domain of medical diagnostics one of high professional and public interest. The major problem of NAFLD diagnostics is that in its initial phase non-alcoholic fatty liver tends to be benign without tendency to progress, while in its second phase -- non-alcoholic steatohepatitis (NASH) can progress to cirrhosis, which subsequently may cause hepatocellular carcinoma. This fact explains the need for more sensitive classifications that would allow early diagnostics of NAFLD. NAFLD diagnostics in most cases is based on clinicopathological criteria -- decision rules expressed through ultarasound signs and laboratory data, annotated by hepatologist/gastroenterologist. In this article we describe the process of creation of a classification of NAFLD early stages based on a decisional reasoning, which combines two methods of medical diagnostics.

Iulian Secrieru
Institute of Mathematics and Computer Science of the Academy of
Sciences of Moldova
5 Academiei Street, Chisinau, MD 2028
Phone: (373 22) 73-81-30
E-mail:

Svetlana Cojocaru
Institute of Mathematics and Computer Science of the Academy of
Sciences of Moldova
5 Academiei Street, Chisinau, MD 2028
Phone: (373 22) 72-84-14
E-mail:

Constantin Gaindric
Institute of Mathematics and Computer Science of the Academy of
Sciences of Moldova
5 Academiei Street, Chisinau, MD 2028
Phone: (373 22) 72-50-12
E-mail:

Olga Popcova
Institute of Mathematics and Computer Science of the Academy of
Sciences of Moldova
5 Academiei Street, Chisinau, MD 2028
Phone: (373 22) 73-81-30
E-mail:

Svetlana Țurcan
State University of Medicine and Pharmacy “Nicolae Testemitanu”
165 Stefan cel Mare Ave., Chisinau, MD 2004
E-mail:

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